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Resources, Facilities, and Support Units
Core Facilities
Core Genotyping Facility
Genome Analysis Unit
Molecular Pathology Unit
Comparative Molecular
Cytogenetics Unit
Clinical Core Facilities
 

Resources, Facilities and Support Units

Core Facilities
Centralized scientific resources have been established to give NCI investigators access to new technologies, special expertise, and additional technical support in fields such as imaging, animal sciences, analytical/protein chemistry, genetics/genomics, and structural biology.

Core Genotyping Facility
The NCI has established a genotyping core resource facility, headed by Dr. Steve Chanock. This facility provides state-of-the-art high throughput genotyping to meet CCR's rapidly expanding needs.

Genome Analysis Unit
This support unit, headed by Dr. Peter FitzGerald, was established to provide genomic analysis and a network for bioinformatics support for the CCR.

Molecular Pathology Unit
This support unit, headed by Dr. Mark Simpson, will provide comparative molecular pathology expertise to CCR scientists who use animal models. The unit will be a central resource for methodologies, protocols and technical development in veterinary clinical pathology.

Comparative Molecular Cytogenetics Unit
This resource core headed by Dr. Roscoe Stanyon, has been established on the NCI Frederick campus to provide molecular cytogenetic support services to the NCI community. The unit will facilitate the assessment of structural and numerical genomic changes in cancer and cancer models.

Clinical Core Facilities

  • Pharmacokinetic/pharmacodynamic Scientific Core Facility, headed by Dr. Doug Figg, performs pharmacokinetic/pharmacodynamic analysis of Phase I and Phase II agents.
  • Preclinical Scientific Support Care, headed by Jane Trepel, provides translational core support services.
  • Molecular Targets Scientific Core is being developed.
  • Clinical Cytogenetics Core, headed by Dr. Diane Arthur, was established by NCI and NHGRI to provide clinical cytogenetics testing, consultation, and counseling necessary for patient diagnosis and management.
  • Immunoassay Core Support has been established to analyze cytolytic T-cell responses to a variety of vaccines developed in NCI laboratories.

Comparative Oncology Program
A significant hurdle in the translation of information from the laboratory to the clinic has been the availability and the effective use of preclinical models of cancer. The CCR – Comparative Oncology Program will compliment a number of new CCR initiatives designed to improve this translational process.

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