The ten-term member sits on the House Transportation and Infrastructure Committee [ majority site | minority site], where he serves as ranking Democrat on the House Subcommittee on Highways, Transit and Pipelines. He also serves on the Aviation and Railroad Subcommittees.

DeFazio also serves on the House Committee on Homeland Security, where he sits on the Subcommittee on Economic Security, Infrastructure Protection and Cybersecurity.

Finally, DeFazio serves on the House Resources Committee, where he sits on the Subcommittee on Forests and Forest Health.

DeFazio and his wife, Myrnie Daut, live in Springfield, OR. He has logged over three million miles traveling between Oregon and Washington, DC, about three times each month, to serve the people of Oregon's Fourth Congressional District in the United States Congress.

One of DeFazio' s proudest accomplishments is the more than $260,000 in after-tax salary he has contributed to education scholarships and to reduce the national debt. Those contributions have funded 157 scholarships for displaced Oregon workers at the five southwestern Oregon community colleges, and the University of Oregon. Since he took office, DeFazio has refused to accept congressional pay raises while the government is deficit spending, and has linked his pay to Social Security cost-of-living adjustments.